Saaim Khan

A selection of stuff I’ve worked on

Some of these are polished. Some are still in-progress. All of them are real.

Long-read sequencing for unsolved hearing loss

At Boston Children’s, I’m working on an Oxford Nanopore protocol and analysis workflow to improve diagnostic yield for kids with idiopathic hearing loss — especially in regions standard panels don’t cover.

Oxford Nanoporeclinical genomicspipelineshearing
Read more

Adaptive sampling + ReadUntil workflows

I’ve been exploring adaptive sampling strategies (ReadUntil) to focus sequencing on the regions that matter, reduce cost/friction, and still keep the output clinically meaningful.

ReadUntiladaptive samplingONT
Read more

Healthcare venture + diligence work

I’ve worked with early-stage funds on sourcing, market research, and diligence — mostly in healthcare and life sciences. A lot of this is pattern recognition + being honest about uncertainty.

diligencehealthcareVCmarket research
Read more

Halal Alpha (quantitative investing)

This is me trying to combine factor modeling / portfolio construction with Sharia-compliant screening — and then stress testing whether it holds up in the real world.

quantscreeningportfolio construction
Read more

NHL data analysis

I’m an avid hockey fan and I like messing around with player/team data. Sometimes it’s xG-ish stuff, sometimes it’s just me trying to make a model stop lying to me.

sports analyticsmodelingPython
Read more

Free Udemy courses (computational + structural bio)

I created two free Udemy courses (intro computational biology research + structural bioinformatics/drug discovery). Somehow they’ve reached 10,000+ learners across 174 countries.

teachingcomputational biologystructural bio
Read more

Walk4Hearing fundraising + advocacy

I helped coordinate/promote New England Walk4Hearing fundraisers via social media and workshops. We raised over $80k across 2022 and 2023.

advocacyhearing lossfundraising
Read more

Museum accessibility consulting (hearing loss exhibit)

I advised on accessibility features for a new hearing loss exhibit at the Boston Museum of Science, and contributed personal perspective on what helps vs what’s performative.

accessibilityDEIhearing loss
Read more